Scholarship: Fully-funded
Degree: Ph.D
Nationality: International Students
Location: UK
Application deadlines: Open
Scholarship Description:
We are seeking a Postdoctoral Research Fellow for a (up-to) 3-year position to work on an exciting project funded by the Medical Research Council (MRC) UKRI and led by Dr Bingxin Lu at the University of Surrey, UK (Deadline 30 April 2025).
The project aims to reconstruct the evolutionary dynamics of chromosomal instability in cancer genomes. Understanding how chromosomal instability evolves during the progression from precancerous lesions to malignancy, metastasis, and treatment resistance is important for cancer detection and treatment.
Building upon our previously published method, CNETML (https://doi.org/10.1186/s13059-023-02983-0), this project will develop more realistic evolutionary models of copy number alterations and better phylogenetic inference methods with wider applicability. The developed methods will then be applied to extensive publicly available datasets to investigate the dynamics of chromosomal instability. Our new methods will enhance the toolkit for cancer researchers and drive broader applications of cancer phylogenetic inference. The insights gained from the inferences will also support personalized therapy and advance public health efforts.
Available Subjects:
- Computational biology.
Eligibility criteria:
- The successful candidate will not only design and conduct the research but also write and communicate results as scientific papers and in scientific presentations at national and international conferences.
Application Procedure:
Please submit your cover letter, CV, and contact of three referenceswith your application on the University of Surrey Website
(http://jobs.surrey.ac.uk/017125).
For informal inquiries, please contact Dr Bingxin Lu
