Nationality: International Students
Application deadlines: Open
The Roulis Laboratory (https://www.med.upenn.edu/roulislab/) was established in the Department of Pathology and Laboratory Medicine at UPenn in July 2023. The lab’s research spans the fields of tissue biology, chronic inflammation, and gastrointestinal cancers. We aim to understand IF and HOW local tissue microenvironments control complex pathogenic processes, with an emphasis on the function of recently discovered fibroblast populations.
We are seeking a highly motivated postdoctoral fellow for a project focusing on the earliest stages of colorectal carcinogenesis and its control by the mesenchymal microenvironment. The project will use genetic mouse models, mouse/human organoids and in vitro fibroblast co-culture systems as platforms to investigate specific cellular and molecular mechanisms that drive tumourigenesis.
- Colon cancer initiation
Candidates are expected to have
- 1) A strong background, demonstrated with first-author publication(s), in a field relevant to cancer biology, immunobiology or stem cell biology,
- 2) Solid technical expertise in mouse genetics and models of disease and/or organoid systems and,
- 3) Proficiency in a wide range of cell biology, molecular and imaging techniques. Team spirit and excellent communication skills in English are essential.
Please send a CV, contact details for three references and a brief statement that summarizes 1) previous research accomplishments, 2) why you are interested in this position and 3) future plans, to Dr. Manolis Roulis at [email protected].