Scholarship: Fully funded
Nationality: International Students
Application deadlines: Open
A postdoctoral fellow position is available at the New York Blood Center to investigate stem cell inflammaging and leukemia in the blood system. The research in PI’s laboratory focuses on the molecular regulation of hematopoietic stem cell function in normal, stress and cancerous conditions. Several research focuses are:
- 1. Latexin signaling in hematopoietic regeneration and leukemia development. We aim to understand the cellular and molecular mechanism by which genetic and pharmaceutical inhibition of latexin regulates HSC aging, regeneration, and leukemia.
- 2. Inflammaging in the regulation of HSC and immune function. We aim to understand how intrinsic and extrinsic inflammation signals regulated HSC and immune aging by focusing on alarmin cytokines.
- 3. Aging niche in the clonal evolution of leukemia stems cell and leukemia development. We aim to understand how the aging niche contributes to the clonal expansion and evolution of age-associated mutant HSC clones and the underlying molecular mechanisms.
- 4. Sex dimorphism in the regulation of normal and malignant hematopoiesis. We aim to understand how sex chromosome-related genes regulate the gender difference in normal HSC function and hematopoiesis as well as in the leukemia etiology.
- stem cell aging and leukemia
- Candidates should have a Ph.D. or equivalent degree and experience with investigating biochemistry, cell biology, molecular biology, as well as mouse models.
- Highly motivated candidates with publication records are encouraged to apply.
- Please email or send applications with a brief statement of research experience and interest, CV, and contact information for at least two references to: [email protected]