Scholarship: Fully funded
Nationality: International Students
Application deadlines: Open
Zhao (https://medschool.cuanschutz.edu/biochemistry/people/primary-faculty/zhao-ning) is based in the Department of Biochemistry and Molecular Genetics at the University of Colorado-Anschutz Medical Campus in Denver, Colorado. The lab aims to understand how aging and disease-related proteins are regulated in their native intracellular environments. Currently, the lab focuses on studying the translation and folding mechanisms of transmembrane proteins at the endoplasmic reticulum, such as ion channel proteins and cell receptors. We use a variety of approaches including state-of-the-art single molecule tracking as well as traditional biochemical and biophysical approaches such as ELISA, Western blots, immunofluorescence, immunoprecipitation, circular dichroism, ITC and DSC. The laboratory is successful in obtaining external funding and is currently funded by NIH K99/R00.
- 1. Postdoc position 1: Tools development for live-cellimaging.The candidate for this position is expected to have extensive experience in designing and engineering proteins. Successful research experience in antibody engineering (scFvs or nanobodies) is a plus. The main focus of this position is developing live cell imaging tools for studying proteintranslation and folding. The candidate is expected to work independently, including but not limited to designing and performing experiments, analyzing data, writing and publishing papers, assisting in grant applications, andmentoring junior scientists in the lab.
- 2. Postdoc position 2: Studying protein translation and folding. The main focus of this position is studying translation and folding mechanisms using the state-of-art single-molecule tracking approach. Candidates with hands-on single-moleculetracking experience are preferred. The candidate is expected to work independently, including but not limited to generating imaging cell lines, designing and performing imaging experiments, analyzing imaging data, writing and publishingpapers, assisting in grant applications, and mentoring junior scientists in the lab.
- PhD in biophysics, biochemistry, or biology-related field
- Experience in single-molecule tracking is preferred
- Experience in imaging analysis using ImageJ and Python is preferred
- Experience in confocal or TIRF fluorescence microscope
- Experience in mammalian cell culturing and generating stable cell lines
- Strong record of peer-reviewed publications
- Fluent in English
Please send the following documents to Dr. Ning Zhao: [email protected]
- Cover letter summarizing past research accomplishmentsand future research interests
- Curriculum vitae
- Contact information for three references